{
  "guidelines": "STYLE.md v0.7",
  "generator": "built-in image_gen; one icon per call",
  "icons": [
    {
      "id": "pi3k-ig",
      "label": "Class IA PI3K",
      "label_zh": "PI3K",
      "prompt": "Create ONE original biomedical protein icon on a true transparent alpha background, square canvas. Flat front-facing 2D vector-like teaching schematic for a coherent PI3K-AKT-mTOR family. Smooth organic closed contours, solid fills only, extremely restrained domain seams. Dark desaturated outline #3D5963, approximately 1.6 units on a 160-unit canvas; inner seams 1.1. Use 2-3 solid colors from teal #69ADB5, gold #E4BE78, lavender #B2A6CD, mint #B3D7CC. Artwork fills central 80% with clear transparent margins. No gradients, highlights, shadows, texture, 3D, white sticker border, text, letters, numbers, arrows, badges, nucleotide symbols, watermark, surrounding diagram or other icons. This is an original domain-level teaching shape, not an atomic model and not copied proprietary artwork. Domains within one protein must form a continuous connected silhouette. Draw class IA PI3K p110alpha catalytic subunit in teal, a broad asymmetrical connected multidomain body with a readable right-side kinase cleft. A smaller gold p85alpha regulatory component hugs the upper-left outside surface. Two tightly assembled protein components, not scattered beads. Exposed regulator recruitment edge at upper left, membrane-facing edge at top. No lipid molecules."
    },
    {
      "id": "akt1-ig",
      "label": "AKT1",
      "label_zh": "AKT1",
      "prompt": "Create ONE original biomedical protein icon on a true transparent alpha background, square canvas. Flat front-facing 2D vector-like teaching schematic for a coherent PI3K-AKT-mTOR family. Smooth organic closed contours, solid fills only, extremely restrained domain seams. Dark desaturated outline #3D5963, approximately 1.6 units on a 160-unit canvas; inner seams 1.1. Use 2-3 solid colors from teal #69ADB5, gold #E4BE78, lavender #B2A6CD, mint #B3D7CC. Artwork fills central 80% with clear transparent margins. No gradients, highlights, shadows, texture, 3D, white sticker border, text, letters, numbers, arrows, badges, nucleotide symbols, watermark, surrounding diagram or other icons. This is an original domain-level teaching shape, not an atomic model and not copied proprietary artwork. Domains within one protein must form a continuous connected silhouette. Draw AKT1 with a small gold N-terminal PH lipid-binding domain on the upper left, a short continuous neck into a larger teal two-lobed kinase body occupying the lower right, and a short lavender regulatory C-tail on the far lower right. PH and kinase are visibly distinct and physically joined. Open substrate cleft at right of kinase and an exposed top edge of PH. No phosphorylation circles."
    },
    {
      "id": "pten-ig",
      "label": "PTEN",
      "label_zh": "PTEN",
      "prompt": "Create ONE original biomedical protein icon on a true transparent alpha background, square canvas. Flat front-facing 2D vector-like teaching schematic for a coherent PI3K-AKT-mTOR family. Smooth organic closed contours, solid fills only, extremely restrained domain seams. Dark desaturated outline #3D5963, approximately 1.6 units on a 160-unit canvas; inner seams 1.1. Use 2-3 solid colors from teal #69ADB5, gold #E4BE78, lavender #B2A6CD, mint #B3D7CC. Artwork fills central 80% with clear transparent margins. No gradients, highlights, shadows, texture, 3D, white sticker border, text, letters, numbers, arrows, badges, nucleotide symbols, watermark, surrounding diagram or other icons. This is an original domain-level teaching shape, not an atomic model and not copied proprietary artwork. Domains within one protein must form a continuous connected silhouette. Draw PTEN as two directly joined domains: teal N-terminal phosphatase domain on left with a shallow upward accessible catalytic cleft, and mint C2 membrane-binding domain on right with a flatter top surface. Short gold C-terminal tail curves down from the right domain. Broad compact silhouette, no gap between domains, no membrane or substrate."
    },
    {
      "id": "pdpk1-ig",
      "label": "PDPK1 (PDK1)",
      "label_zh": "PDPK1",
      "prompt": "Create ONE original biomedical protein icon on a true transparent alpha background, square canvas. Flat front-facing 2D vector-like teaching schematic for a coherent PI3K-AKT-mTOR family. Smooth organic closed contours, solid fills only, extremely restrained domain seams. Dark desaturated outline #3D5963, approximately 1.6 units on a 160-unit canvas; inner seams 1.1. Use 2-3 solid colors from teal #69ADB5, gold #E4BE78, lavender #B2A6CD, mint #B3D7CC. Artwork fills central 80% with clear transparent margins. No gradients, highlights, shadows, texture, 3D, white sticker border, text, letters, numbers, arrows, badges, nucleotide symbols, watermark, surrounding diagram or other icons. This is an original domain-level teaching shape, not an atomic model and not copied proprietary artwork. Domains within one protein must form a continuous connected silhouette. Draw PDPK1 protein kinase with a large teal bilobed N-terminal kinase body at left, an accessible substrate cleft on its upper-left contour, and a smaller gold C-terminal PH domain at lower right joined by a short organic neck. Distinct from AKT: kinase left, PH right, no long terminal tail. Two colors, no phosphates, no pyruvate complex."
    },
    {
      "id": "mtor-ig",
      "label": "mTOR",
      "label_zh": "mTOR",
      "prompt": "Create ONE original biomedical protein icon on a true transparent alpha background, square canvas. Flat front-facing 2D vector-like teaching schematic for a coherent PI3K-AKT-mTOR family. Smooth organic closed contours, solid fills only, extremely restrained domain seams. Dark desaturated outline #3D5963, approximately 1.6 units on a 160-unit canvas; inner seams 1.1. Use 2-3 solid colors from teal #69ADB5, gold #E4BE78, lavender #B2A6CD, mint #B3D7CC. Artwork fills central 80% with clear transparent margins. No gradients, highlights, shadows, texture, 3D, white sticker border, text, letters, numbers, arrows, badges, nucleotide symbols, watermark, surrounding diagram or other icons. This is an original domain-level teaching shape, not an atomic model and not copied proprietary artwork. Domains within one protein must form a continuous connected silhouette. Draw mTOR as a substantial open C-shaped teal HEAT-repeat solenoid with just three broad internal segment seams, connected continuously to a lavender FAT-kinase region at lower right. Large empty concave space opens toward the left. Shallow catalytic cleft at far right of lavender region. A broad external upper-left solenoid surface can contact RAPTOR; an external bottom-left solenoid surface can contact RHEB, away from kinase cleft; lower-right kinase flank can contact mLST8. All parts one connected protein, no extra components or labels."
    },
    {
      "id": "raptor-ig",
      "label": "RAPTOR",
      "label_zh": "RAPTOR",
      "prompt": "Create ONE original biomedical protein icon on a true transparent alpha background, square canvas. Flat front-facing 2D vector-like teaching schematic for a coherent PI3K-AKT-mTOR family. Smooth organic closed contours, solid fills only, extremely restrained domain seams. Dark desaturated outline #3D5963, approximately 1.6 units on a 160-unit canvas; inner seams 1.1. Use 2-3 solid colors from teal #69ADB5, gold #E4BE78, lavender #B2A6CD, mint #B3D7CC. Artwork fills central 80% with clear transparent margins. No gradients, highlights, shadows, texture, 3D, white sticker border, text, letters, numbers, arrows, badges, nucleotide symbols, watermark, surrounding diagram or other icons. This is an original domain-level teaching shape, not an atomic model and not copied proprietary artwork. Domains within one protein must form a continuous connected silhouette. Draw RAPTOR scaffold as an elongated gently curved teal body running upper left to lower right, with a rounded gold C-terminal WD40 domain at the lower right continuously joined. Shape like a compact curved bracket with a broad concave left-side surface to fit the outside of mTOR. Only two broad internal domain seams, not beads. No labels or partners."
    },
    {
      "id": "mlst8-ig",
      "label": "mLST8",
      "label_zh": "mLST8",
      "prompt": "Create ONE original biomedical protein icon on a true transparent alpha background, square canvas. Flat front-facing 2D vector-like teaching schematic for a coherent PI3K-AKT-mTOR family. Smooth organic closed contours, solid fills only, extremely restrained domain seams. Dark desaturated outline #3D5963, approximately 1.6 units on a 160-unit canvas; inner seams 1.1. Use 2-3 solid colors from teal #69ADB5, gold #E4BE78, lavender #B2A6CD, mint #B3D7CC. Artwork fills central 80% with clear transparent margins. No gradients, highlights, shadows, texture, 3D, white sticker border, text, letters, numbers, arrows, badges, nucleotide symbols, watermark, surrounding diagram or other icons. This is an original domain-level teaching shape, not an atomic model and not copied proprietary artwork. Domains within one protein must form a continuous connected silhouette. Draw mLST8 as a compact seven-bladed WD40 beta-propeller teaching silhouette. Lavender rounded scalloped disc with seven broad subtly differentiated lobes and very simple dark radial internal seams toward a small filled teal center. No literal central hole, no gear teeth, no perspective. A small shallow flattened contact edge at upper left for kinase-flank association."
    },
    {
      "id": "rheb-ig",
      "label": "RHEB",
      "label_zh": "RHEB",
      "prompt": "Create ONE original biomedical protein icon on a true transparent alpha background, square canvas. Flat front-facing 2D vector-like teaching schematic for a coherent PI3K-AKT-mTOR family. Smooth organic closed contours, solid fills only, extremely restrained domain seams. Dark desaturated outline #3D5963, approximately 1.6 units on a 160-unit canvas; inner seams 1.1. Use 2-3 solid colors from teal #69ADB5, gold #E4BE78, lavender #B2A6CD, mint #B3D7CC. Artwork fills central 80% with clear transparent margins. No gradients, highlights, shadows, texture, 3D, white sticker border, text, letters, numbers, arrows, badges, nucleotide symbols, watermark, surrounding diagram or other icons. This is an original domain-level teaching shape, not an atomic model and not copied proprietary artwork. Domains within one protein must form a continuous connected silhouette. Draw small GTPase RHEB as a compact asymmetrical teal globular body with two subtle switch-region seams, a shallow accessible contact indentation at right, and a short gold C-terminal prenylated tail extending upward left to a single small lipid tip. Continuous tail attachment. Two colors. Distinct from a generic circular blob. No GDP or GTP, no nucleotides, no membrane, no badges."
    }
  ]
}